Tianyan Chi Selected Research

Stroke (Strokes)

1/2023	Sigma-1 Receptor Activation Improves Oligodendrogenesis and Promotes White-Matter Integrity after Stroke in Mice with Diabetic Mellitus.
1/2022	Sigma-1 receptor activation alleviates blood-brain barrier disruption post cerebral ischemia stroke by stimulating the GDNF-GFRα1-RET pathway.

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Tianyan Chi Research Topics

Disease

9	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 11/2012
8	Cognitive Dysfunction 11/2021 - 05/2013
5	Memory Disorders (Memory Loss) 06/2020 - 05/2013
3	Brain Ischemia (Cerebral Ischemia) 01/2023 - 01/2019
3	Neuroinflammatory Diseases 01/2022 - 11/2016
2	Stroke (Strokes) 01/2023 - 01/2022
2	Inflammation (Inflammations) 01/2022 - 10/2014
2	Dementia (Dementias) 01/2020 - 01/2016
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2019 - 05/2013
1	Demyelinating Diseases (Demyelinating Disease) 01/2023
1	Type 2 Diabetes Mellitus (MODY) 01/2023
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2022
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2020
1	Reperfusion Injury 01/2019
1	Huntington Disease (Huntington's Disease) 01/2019
1	Muscle Weakness 10/2018
1	Ischemia 03/2018
1	Ischemic Stroke 03/2018
1	Rheumatic Diseases (Rheumatism) 01/2016
1	Melanoma (Melanoma, Malignant) 10/2014
1	Neoplasms (Cancer) 10/2014

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 01/2023 - 05/2013
5	xanthocerasideIBA 05/2019 - 05/2013
4	Amyloid (Amyloid Fibrils)IBA 01/2022 - 11/2016
3	Sigma-1 ReceptorIBA 01/2023 - 01/2019
3	tolfenamic acidIBA 06/2020 - 10/2018
2	Streptozocin (Streptozotocin)FDA Link 01/2023 - 05/2013
2	CytokinesIBA 01/2022 - 10/2018
2	Bexarotene (LGD1069)FDA Link 11/2021 - 01/2019
2	Glutamic Acid (Glutamate)FDA Link 10/2018 - 01/2018
2	Insulin (Novolin)FDA Link 10/2014 - 05/2013
2	SaponinsIBA 10/2014 - 05/2013
1	Peptides (Polypeptides)IBA 01/2023
1	2- (4- morpholino)ethyl- 1- phenylcyclohexane- 1- carboxylateIBA 01/2023
1	Endothelin-1 (Endothelin 1)IBA 01/2023
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2023
1	AntigensIBA 01/2023
1	Blood Glucose (Blood Sugar)IBA 01/2023
1	2',3'-Cyclic-Nucleotide Phosphodiesterases (2',3' Cyclic Nucleotide Phosphodiesterase)IBA 01/2023
1	Vasoconstrictor AgentsIBA 01/2023
1	NucleotidesIBA 01/2023
1	Phosphotransferases (Kinase)IBA 01/2022
1	PTEN-induced putative kinaseIBA 01/2022
1	Protein Kinases (Protein Kinase)IBA 06/2020
1	CyclinsIBA 06/2020
1	Neutralizing AntibodiesIBA 01/2020
1	interleukin-1beta-converting enzyme inhibitorIBA 01/2020
1	Aldehyde Reductase (Aldose Reductase)IBA 01/2020
1	InterleukinsIBA 01/2020
1	InflammasomesIBA 01/2020
1	Small Interfering RNA (siRNA)IBA 01/2020
1	Interleukin-18 (Interleukin 18)IBA 01/2020
1	Presenilin-1IBA 01/2019
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2019
1	Protein Kinase CIBA 01/2019
1	BerberineIBA 01/2019
1	Neuroprotective AgentsIBA 10/2018
1	OccludinIBA 03/2018
1	Evans Blue (Blue, Evans)FDA Link 03/2018
1	SynaptophysinIBA 03/2018
1	Disks Large Homolog 4 ProteinIBA 03/2018
1	Claudin-5IBA 03/2018
1	Tight Junction ProteinsIBA 03/2018
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2018
1	CalciumIBA 01/2018
1	Memantine (Namenda)FDA Link 11/2016
1	GIBH-130IBA 11/2016
1	Donepezil (Aricept)FDA LinkGeneric 11/2016
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 01/2016
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2016
1	Growth Factor ReceptorsIBA 10/2014
1	CaspasesIBA 10/2014
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 10/2014
1	TriterpenesIBA 05/2013
1	aminopyridazineIBA 11/2012
1	Therapeutic UsesIBA 11/2012

Therapy/Procedure

1	Traditional Medicine (Folk Remedies) 01/2016